diff --git a/src/lightning/fabric/CHANGELOG.md b/src/lightning/fabric/CHANGELOG.md
index 34a5d838fd33a..aa909630cfbd8 100644
--- a/src/lightning/fabric/CHANGELOG.md
+++ b/src/lightning/fabric/CHANGELOG.md
@@ -17,6 +17,8 @@ The format is based on [Keep a Changelog](http://keepachangelog.com/en/1.0.0/).
 
 ### Fixed
 
+- Fixed `DistributedSamplerWrapper` not forwarding `set_epoch` to the underlying sampler ([#21454](https://github.com/Lightning-AI/pytorch-lightning/pull/21454))
+
 - Fixed DDP notebook CUDA fork check to allow passive initialization when CUDA is not actively used ([#21402](https://github.com/Lightning-AI/pytorch-lightning/pull/21402))
 
 ### Removed
diff --git a/src/lightning/fabric/utilities/distributed.py b/src/lightning/fabric/utilities/distributed.py
index a5f9f7457862e..d57dcdde75475 100644
--- a/src/lightning/fabric/utilities/distributed.py
+++ b/src/lightning/fabric/utilities/distributed.py
@@ -372,6 +372,14 @@ def __iter__(self) -> Iterator:
         self.dataset.reset()
         return (self.dataset[index] for index in super().__iter__())
 
+    @override
+    def set_epoch(self, epoch: int) -> None:
+        super().set_epoch(epoch)
+        # Forward set_epoch to the original sampler if it supports it
+        original_sampler = self.dataset._sampler
+        if hasattr(original_sampler, "set_epoch") and callable(original_sampler.set_epoch):
+            original_sampler.set_epoch(epoch)
+
 
 def _suggested_max_num_threads(num_processes: int = 1) -> int:
     if num_processes < 1:
diff --git a/tests/tests_fabric/utilities/test_distributed.py b/tests/tests_fabric/utilities/test_distributed.py
index 51c4b320d5525..532c7c6d19024 100644
--- a/tests/tests_fabric/utilities/test_distributed.py
+++ b/tests/tests_fabric/utilities/test_distributed.py
@@ -15,6 +15,7 @@
 from lightning.fabric.strategies import DDPStrategy, SingleDeviceStrategy
 from lightning.fabric.strategies.launchers.multiprocessing import _MultiProcessingLauncher
 from lightning.fabric.utilities.distributed import (
+    DistributedSamplerWrapper,
     _destroy_dist_connection,
     _gather_all_tensors,
     _get_default_process_group_backend_for_device,
@@ -274,3 +275,73 @@ def test_is_dtensor(monkeypatch):
 
     monkeypatch.setattr(lightning.fabric.utilities.distributed, "_TORCH_GREATER_EQUAL_2_4", False)
     assert not _is_dtensor(Mock(spec=DTensor))
+
+
+class _CustomSampler(torch.utils.data.Sampler):
+    """A custom sampler for testing DistributedSamplerWrapper."""
+
+    def __init__(self, data_source, non_callable_set_epoch: bool = False):
+        self.data_source = data_source
+        if non_callable_set_epoch:
+            self.set_epoch = "not a method"  # attribute exists but is not callable
+
+    def __len__(self):
+        return len(self.data_source)
+
+    def __iter__(self):
+        return iter(range(len(self.data_source)))
+
+
+class _CustomSamplerWithSetEpoch(_CustomSampler):
+    """A custom sampler that tracks set_epoch calls for testing."""
+
+    def __init__(self, data_source):
+        super().__init__(data_source)
+        self.epoch = 0
+        self.set_epoch_call_count = 0
+
+    def set_epoch(self, epoch):
+        self.epoch = epoch
+        self.set_epoch_call_count += 1
+
+
+def test_distributed_sampler_wrapper_set_epoch():
+    """Test that DistributedSamplerWrapper correctly handles set_epoch for various sampler types.
+
+    Reproduces issue #21454: When a sampler is wrapped by DistributedSamplerWrapper, calling set_epoch on the wrapper
+    should forward the call to the underlying sampler if it supports the method.
+
+    """
+    data_source = list(range(100))
+
+    # Case 1: Sampler WITH set_epoch method - should forward the call
+    sampler_with_set_epoch = _CustomSamplerWithSetEpoch(data_source)
+    wrapper = DistributedSamplerWrapper(sampler_with_set_epoch, num_replicas=2, rank=0)
+
+    assert sampler_with_set_epoch.epoch == 0
+    assert sampler_with_set_epoch.set_epoch_call_count == 0
+
+    wrapper.set_epoch(5)
+    assert wrapper.epoch == 5
+    assert sampler_with_set_epoch.epoch == 5, "set_epoch was not forwarded to the underlying sampler"
+    assert sampler_with_set_epoch.set_epoch_call_count == 1
+
+    wrapper.set_epoch(10)
+    assert wrapper.epoch == 10
+    assert sampler_with_set_epoch.epoch == 10
+    assert sampler_with_set_epoch.set_epoch_call_count == 2
+
+    # Case 2: Sampler WITHOUT set_epoch method - should not fail
+    sampler_without_set_epoch = _CustomSampler(data_source)
+    wrapper = DistributedSamplerWrapper(sampler_without_set_epoch, num_replicas=2, rank=0)
+
+    wrapper.set_epoch(5)  # Should not raise
+    assert wrapper.epoch == 5
+
+    # Case 3: Sampler with non-callable set_epoch attribute - should not fail or call it
+    sampler_non_callable = _CustomSampler(data_source, non_callable_set_epoch=True)
+    wrapper = DistributedSamplerWrapper(sampler_non_callable, num_replicas=2, rank=0)
+
+    wrapper.set_epoch(5)  # Should not raise
+    assert wrapper.epoch == 5
+    assert sampler_non_callable.set_epoch == "not a method"  # Should remain unchanged