diff --git a/docroot/profiles/custom/cgov_site/modules/custom/cgov_yaml_content/content/16100_biography-stephen-chanock.content.yml b/docroot/profiles/custom/cgov_site/modules/custom/cgov_yaml_content/content/16100_biography-stephen-chanock.content.yml
index 680fd7bac2..74f24354a0 100644
--- a/docroot/profiles/custom/cgov_site/modules/custom/cgov_yaml_content/content/16100_biography-stephen-chanock.content.yml
+++ b/docroot/profiles/custom/cgov_site/modules/custom/cgov_yaml_content/content/16100_biography-stephen-chanock.content.yml
@@ -14,7 +14,7 @@
         args:
           - 'image'
           - type: 'module'
-            filename: '2059-160x140.jpg'
+            filename: 'biographies-chanock.png'
       alt: 'Stephen J. Chanock, M.D.'
 - entity: "node"
   type: "cgov_biography"
diff --git a/docroot/profiles/custom/cgov_site/modules/custom/cgov_yaml_content/images/2059-160x140.jpg b/docroot/profiles/custom/cgov_site/modules/custom/cgov_yaml_content/images/2059-160x140.jpg
deleted file mode 100644
index 65de178776..0000000000
Binary files a/docroot/profiles/custom/cgov_site/modules/custom/cgov_yaml_content/images/2059-160x140.jpg and /dev/null differ
diff --git a/docroot/profiles/custom/cgov_site/modules/custom/cgov_yaml_content/images/biographies-chanock.png b/docroot/profiles/custom/cgov_site/modules/custom/cgov_yaml_content/images/biographies-chanock.png
new file mode 100644
index 0000000000..ae92cd438b
Binary files /dev/null and b/docroot/profiles/custom/cgov_site/modules/custom/cgov_yaml_content/images/biographies-chanock.png differ
diff --git a/docroot/profiles/custom/cgov_site/modules/custom/cgov_yaml_content/images/dr_chanock_headshot.png b/docroot/profiles/custom/cgov_site/modules/custom/cgov_yaml_content/images/dr_chanock_headshot.png
deleted file mode 100644
index cd16d7980b..0000000000
Binary files a/docroot/profiles/custom/cgov_site/modules/custom/cgov_yaml_content/images/dr_chanock_headshot.png and /dev/null differ
diff --git a/docroot/profiles/custom/cgov_site/themes/custom/cgov/src/styles/_profile-panel.scss b/docroot/profiles/custom/cgov_site/themes/custom/cgov/src/styles/_profile-panel.scss
deleted file mode 100644
index 8958a0e218..0000000000
--- a/docroot/profiles/custom/cgov_site/themes/custom/cgov/src/styles/_profile-panel.scss
+++ /dev/null
@@ -1,192 +0,0 @@
-.profile-panel {
-  .slot-item {
-    background: $white;
-    border: 1px solid $yetAnotherGrey;
-    box-shadow: 0 0 9px 1px rgba(0, 0, 0, 0.15);
-    display: flex;
-    flex-direction: column;
-    justify-content: flex-start;
-    margin: 1.3em 0 0 0;
-    overflow: hidden;
-    padding: 25px;
-    width: 100%;
-
-    @include break(medium) {
-      flex-direction: row;
-    }
-  }
-
-  &-image {
-    flex: none;
-    margin-bottom: 16px;
-    max-width: 206px;
-    text-align: center;
-    width: 206px;
-  }
-
-  &-content {
-    color: $dgrey00;
-    flex: 1 1 auto;
-    font-family: $montserrat-font-stack;
-    font-size: 16px;
-    line-height: 1.5;
-    padding: 0;
-    word-wrap: break-word;
-
-    h1 {
-      margin-top: 0;
-    }
-
-    .profile-title {
-      font-size: 18px;
-      line-height: 1.33;
-
-      &:last-of-type {
-        margin-bottom: 1.25em;
-      }
-    }
-
-    .profile-orgs,
-    .profile-titles {
-      margin-bottom: 1.25em;
-    }
-
-    p {
-      font-size: 16px;
-      line-height: 1.5;
-    }
-
-    @include break(medium) {
-      padding-left: 25px;
-    }
-  }
-
-  .contact-divider {
-    display: none;
-    margin: 0 5px;
-
-    @include break(medium) {
-      display: inline-block;
-    }
-  }
-
-  &-social-media {
-    @include break(medium) {
-      display: flex;
-      flex-direction: row;
-      width: 100%;
-    }
-  }
-
-  .profile-contact-info {
-    margin-bottom: 1.25em;
-
-    @include break(medium) {
-      & > div {
-        display: inline-block;
-      }
-    }
-  }
-
-  .profile-social-link {
-    display: inline-block;
-    height: 35px;
-    margin-bottom: 15px;
-    margin-right: 20px;
-    width: 35px;
-
-    @include break(medium) {
-      align-items: center;
-      display: flex;
-    }
-
-    .icon {
-      background: $dteal;
-      border-radius: 50%;
-      display: inline-block;
-      height: 35px;
-      position: relative;
-      width: 35px;
-
-      &::after {
-        content: "";
-        display: inline-block;
-        font-size: 1.1em;
-        height: 28px;
-        left: 0;
-        right: 0;
-        margin: 0 auto;
-        position: absolute;
-        top: 2px;
-        width: 25px;
-      }
-    }
-
-    &.twitter {
-      @include break(medium) {
-        flex: none;
-      }
-
-      .icon {
-        &::after {
-          @include svg-sprite(twitter-x-white, bg);
-          width: 20px;
-          height: 20px;
-          top: 8px;
-        }
-      }
-    }
-
-    &.linkedin {
-      @include break(medium) {
-        flex: none;
-      }
-
-      .icon {
-        &::after {
-          @include svg-sprite(linkedin-white, bg);
-          width: 17px;
-          height: 17px;
-          top: 8px;
-        }
-      }
-    }
-
-    &.publications {
-      align-items: center;
-      display: flex;
-      flex: 1 1 auto;
-      margin-right: 0;
-      width: 100%;
-
-      .icon {
-        display: inline-block;
-        margin-right: 10px;
-
-        &::after {
-          @include svg-sprite(file-icon, bg);
-        }
-      }
-    }
-  }
-}
-
-.press-contact {
-  background: $white;
-  border: 1px solid $yetAnotherGrey;
-  box-shadow: 0 0 9px 1px rgba(0, 0, 0, 0.15);
-  margin: 1.3em 0 1.5em 0;
-  padding: 15px;
-
-  h2 {
-    color: $dgrey00;
-    font-size: 23px;
-    margin-top: 0;
-  }
-
-  p {
-    &:last-child {
-      margin-bottom: 0;
-    }
-  }
-}
diff --git a/docroot/profiles/custom/cgov_site/themes/custom/ncids_trans/front-end/src/entrypoints/biography/biography-legacy.scss b/docroot/profiles/custom/cgov_site/themes/custom/ncids_trans/front-end/src/entrypoints/biography/biography-legacy.scss
index d2a8f379c9..2ba2c70924 100644
--- a/docroot/profiles/custom/cgov_site/themes/custom/ncids_trans/front-end/src/entrypoints/biography/biography-legacy.scss
+++ b/docroot/profiles/custom/cgov_site/themes/custom/ncids_trans/front-end/src/entrypoints/biography/biography-legacy.scss
@@ -9,7 +9,6 @@
 @import '../../legacy/styles/variables';
 @import '../../legacy/styles/breakpoint-mixins';
 @import '~Styles/sprites/svg-sprite';
-@import '~Core/styles/profile-panel';
 
 // Override wrapper styles for embedded images
 // (Specifically the figure and caption/credit/enlarge styles
@@ -18,3 +17,25 @@
 @import '../../legacy/transition-hacks/inner-page-embed-feature-card-hack';
 @import '../../legacy/transition-hacks/inner-page-embed-entity-hack';
 @import '../../legacy/transition-hacks/inner-page-embed-infographic-hack';
+
+// Styles for press contact that was located in profile-panel
+.press-contact {
+	background: $white;
+	border: 1px solid $yetAnotherGrey;
+	box-shadow: 0 0 9px 1px rgba(0, 0, 0, 0.15);
+	margin: 1.3em 0 1.5em 0;
+	padding: 15px;
+
+	h2 {
+		color: $dgrey00;
+		font-size: 23px;
+		margin-top: 0;
+	}
+
+	p {
+		&:last-child {
+			margin-bottom: 0;
+		}
+	}
+}
+
diff --git a/docroot/profiles/custom/cgov_site/themes/custom/ncids_trans/front-end/src/entrypoints/biography/biography.scss b/docroot/profiles/custom/cgov_site/themes/custom/ncids_trans/front-end/src/entrypoints/biography/biography.scss
index 1e2f1b8d2b..19636d2f66 100644
--- a/docroot/profiles/custom/cgov_site/themes/custom/ncids_trans/front-end/src/entrypoints/biography/biography.scss
+++ b/docroot/profiles/custom/cgov_site/themes/custom/ncids_trans/front-end/src/entrypoints/biography/biography.scss
@@ -6,6 +6,7 @@
 @forward '../../lib/components/cgdp-article-footer/';
 @forward '../../lib/components/cgdp-related-resources';
 @forward '../../lib/components/cgdp-document-dates';
+@forward '../../lib/components/cgdp-profile-box';
 @forward '../../lib/components/wysiwyg/common/cgdp-embed-image';
 @forward '../../lib/components/wysiwyg/common/cgdp-embed-infographic';
 @forward '../../lib/components/wysiwyg/common/cgdp-embed-video';
diff --git a/docroot/profiles/custom/cgov_site/themes/custom/ncids_trans/front-end/src/entrypoints/cancer-center/cancer-center-legacy.scss b/docroot/profiles/custom/cgov_site/themes/custom/ncids_trans/front-end/src/entrypoints/cancer-center/cancer-center-legacy.scss
index d2a8f379c9..a3d1c6bd76 100644
--- a/docroot/profiles/custom/cgov_site/themes/custom/ncids_trans/front-end/src/entrypoints/cancer-center/cancer-center-legacy.scss
+++ b/docroot/profiles/custom/cgov_site/themes/custom/ncids_trans/front-end/src/entrypoints/cancer-center/cancer-center-legacy.scss
@@ -9,7 +9,6 @@
 @import '../../legacy/styles/variables';
 @import '../../legacy/styles/breakpoint-mixins';
 @import '~Styles/sprites/svg-sprite';
-@import '~Core/styles/profile-panel';
 
 // Override wrapper styles for embedded images
 // (Specifically the figure and caption/credit/enlarge styles
diff --git a/docroot/profiles/custom/cgov_site/themes/custom/ncids_trans/front-end/src/entrypoints/cancer-center/cancer-center.scss b/docroot/profiles/custom/cgov_site/themes/custom/ncids_trans/front-end/src/entrypoints/cancer-center/cancer-center.scss
index 6f0fc4f2f9..dba1427a92 100644
--- a/docroot/profiles/custom/cgov_site/themes/custom/ncids_trans/front-end/src/entrypoints/cancer-center/cancer-center.scss
+++ b/docroot/profiles/custom/cgov_site/themes/custom/ncids_trans/front-end/src/entrypoints/cancer-center/cancer-center.scss
@@ -6,6 +6,7 @@
 @forward '../../lib/components/cgdp-article-footer/';
 @forward '../../lib/components/cgdp-related-resources';
 @forward '../../lib/components/cgdp-document-dates';
+@forward '../../lib/components/cgdp-profile-box';
 @forward '../../lib/components/wysiwyg/common/cgdp-embed-image';
 @forward '../../lib/components/wysiwyg/common/cgdp-embed-infographic';
 @forward '../../lib/components/wysiwyg/common/cgdp-embed-video';
diff --git a/docroot/profiles/custom/cgov_site/themes/custom/ncids_trans/front-end/src/lib/components/cgdp-profile-box/cgdp-profile-box.ts b/docroot/profiles/custom/cgov_site/themes/custom/ncids_trans/front-end/src/lib/components/cgdp-profile-box/cgdp-profile-box.ts
new file mode 100644
index 0000000000..3c44b3b907
--- /dev/null
+++ b/docroot/profiles/custom/cgov_site/themes/custom/ncids_trans/front-end/src/lib/components/cgdp-profile-box/cgdp-profile-box.ts
@@ -0,0 +1,4 @@
+const initialize = () => {
+	//
+};
+export default initialize;
diff --git a/docroot/profiles/custom/cgov_site/themes/custom/ncids_trans/front-end/src/lib/components/cgdp-profile-box/index.scss b/docroot/profiles/custom/cgov_site/themes/custom/ncids_trans/front-end/src/lib/components/cgdp-profile-box/index.scss
new file mode 100644
index 0000000000..ad5e87fd70
--- /dev/null
+++ b/docroot/profiles/custom/cgov_site/themes/custom/ncids_trans/front-end/src/lib/components/cgdp-profile-box/index.scss
@@ -0,0 +1,37 @@
+@forward 'usa-icon';
+@use 'uswds-core' as *;
+
+.cgdp-profile-box {
+	@include u-shadow(2);
+	@include u-radius('md');
+	@include u-padding(3);
+
+	// TODO we should just expect good images, right?
+	img {
+		max-width: 100%;
+		height: auto;
+	}
+
+	.cgdp-profile-box__heading {
+		@include typeset-h1;
+		margin: 0 0 units(2);
+	}
+
+	.cgdp-profile-box__title {
+		font-size: size("body", "sm");
+	}
+
+	.cgdp-profile-box__titles,
+	.cgdp-profile-box__org {
+		@include unstyled-list;
+		@include u-margin-y(2);
+	}
+
+	.cgdp-profile-box__address,
+	.cgdp-profile-box__phone,
+	.cgdp-profile-box__publications,
+	.cgdp-profile-box__social-media,
+	.cgdp-profile-box__website {
+		@include u-margin-y(2);
+	}
+}
diff --git a/docroot/profiles/custom/cgov_site/themes/custom/ncids_trans/front-end/src/lib/components/cgdp-profile-box/index.ts b/docroot/profiles/custom/cgov_site/themes/custom/ncids_trans/front-end/src/lib/components/cgdp-profile-box/index.ts
new file mode 100644
index 0000000000..506ebf3768
--- /dev/null
+++ b/docroot/profiles/custom/cgov_site/themes/custom/ncids_trans/front-end/src/lib/components/cgdp-profile-box/index.ts
@@ -0,0 +1,3 @@
+// Passthrough for cleaner imports.
+import initialize from './cgdp-profile-box';
+export default initialize;
diff --git a/docroot/profiles/custom/cgov_site/themes/custom/ncids_trans/templates/content/biography/field--field-campus.html.twig b/docroot/profiles/custom/cgov_site/themes/custom/ncids_trans/templates/content/biography/field--field-campus.html.twig
index f36f82c862..18e9f3ea64 100644
--- a/docroot/profiles/custom/cgov_site/themes/custom/ncids_trans/templates/content/biography/field--field-campus.html.twig
+++ b/docroot/profiles/custom/cgov_site/themes/custom/ncids_trans/templates/content/biography/field--field-campus.html.twig
@@ -1,3 +1,3 @@
 {% for item in items %}
-    {{ item.content }}
-{% endfor %}
\ No newline at end of file
+  {{ item.content }}
+{% endfor %}
diff --git a/docroot/profiles/custom/cgov_site/themes/custom/ncids_trans/templates/content/biography/field--field-email-address.html.twig b/docroot/profiles/custom/cgov_site/themes/custom/ncids_trans/templates/content/biography/field--field-email-address.html.twig
index 2e6a2ff2c9..37b4b3b39a 100644
--- a/docroot/profiles/custom/cgov_site/themes/custom/ncids_trans/templates/content/biography/field--field-email-address.html.twig
+++ b/docroot/profiles/custom/cgov_site/themes/custom/ncids_trans/templates/content/biography/field--field-email-address.html.twig
@@ -1,7 +1,5 @@
 {% for item in items %}
-    <div class="profile-contact-email">
-        <a href="mailto:{{- item.content -}}">
-            {{ item.content }}
-        </a>
-    </div>
+  <a href="mailto:{{- item.content -}}">
+    {{ item.content }}
+  </a>
 {% endfor %}
diff --git a/docroot/profiles/custom/cgov_site/themes/custom/ncids_trans/templates/content/biography/field--field-linkedin-handle.html.twig b/docroot/profiles/custom/cgov_site/themes/custom/ncids_trans/templates/content/biography/field--field-linkedin-handle.html.twig
index 87bc312387..65378e8827 100644
--- a/docroot/profiles/custom/cgov_site/themes/custom/ncids_trans/templates/content/biography/field--field-linkedin-handle.html.twig
+++ b/docroot/profiles/custom/cgov_site/themes/custom/ncids_trans/templates/content/biography/field--field-linkedin-handle.html.twig
@@ -1,6 +1,6 @@
 {% for item in items %}
-    <a href="http://www.linkedin.com/in/{{- item.content -}}" class="profile-social-link linkedin no-exit-notification">
-        <i class="icon" aria-hidden="true"></i>
-        <span class="show-for-sr">Connect with me on LinkedIn</span>
-    </a>
-{% endfor %}
\ No newline at end of file
+  <a href="http://www.linkedin.com/in/{{- item.content -}}" class="cgdp-profile-box__linkedin no-exit-notification">
+    <i class="icon" aria-hidden="true"></i>
+    <span class="show-for-sr">Connect with me on LinkedIn</span>
+  </a>
+{% endfor %}
diff --git a/docroot/profiles/custom/cgov_site/themes/custom/ncids_trans/templates/content/biography/field--field-office-location.html.twig b/docroot/profiles/custom/cgov_site/themes/custom/ncids_trans/templates/content/biography/field--field-office-location.html.twig
index d5e61556cd..18e9f3ea64 100644
--- a/docroot/profiles/custom/cgov_site/themes/custom/ncids_trans/templates/content/biography/field--field-office-location.html.twig
+++ b/docroot/profiles/custom/cgov_site/themes/custom/ncids_trans/templates/content/biography/field--field-office-location.html.twig
@@ -1,3 +1,3 @@
 {% for item in items %}
-    {{ item.content }}
+  {{ item.content }}
 {% endfor %}
diff --git a/docroot/profiles/custom/cgov_site/themes/custom/ncids_trans/templates/content/biography/field--field-phone-number.html.twig b/docroot/profiles/custom/cgov_site/themes/custom/ncids_trans/templates/content/biography/field--field-phone-number.html.twig
index 422576523f..18e9f3ea64 100644
--- a/docroot/profiles/custom/cgov_site/themes/custom/ncids_trans/templates/content/biography/field--field-phone-number.html.twig
+++ b/docroot/profiles/custom/cgov_site/themes/custom/ncids_trans/templates/content/biography/field--field-phone-number.html.twig
@@ -1,3 +1,3 @@
 {% for item in items %}
-  <div class="profile-contact-phone">{{ item.content }}</div>
-{% endfor %}
\ No newline at end of file
+  {{ item.content }}
+{% endfor %}
diff --git a/docroot/profiles/custom/cgov_site/themes/custom/ncids_trans/templates/content/biography/field--field-scientific-publications.html.twig b/docroot/profiles/custom/cgov_site/themes/custom/ncids_trans/templates/content/biography/field--field-scientific-publications.html.twig
index 95876bbcdf..b1941feb14 100644
--- a/docroot/profiles/custom/cgov_site/themes/custom/ncids_trans/templates/content/biography/field--field-scientific-publications.html.twig
+++ b/docroot/profiles/custom/cgov_site/themes/custom/ncids_trans/templates/content/biography/field--field-scientific-publications.html.twig
@@ -1,7 +1,3 @@
 {% for item in items %}
-    <a href="{{- item.content -}}" class="profile-social-link publications no-exit-notification">
-        <i class="icon publications" aria-hidden="true"></i>
-        <span class="show-for-sr">View my </span>
-        <span>Scientific Publications</span>
-    </a>
-{% endfor %}
\ No newline at end of file
+  <a href="{{- item.content -}}" class="cgdp-profile-box__publications no-exit-notification">Scientific Publications</a>
+{% endfor %}
diff --git a/docroot/profiles/custom/cgov_site/themes/custom/ncids_trans/templates/content/biography/field--field-title.html.twig b/docroot/profiles/custom/cgov_site/themes/custom/ncids_trans/templates/content/biography/field--field-title.html.twig
index f2ddf3e0af..bc8771393a 100644
--- a/docroot/profiles/custom/cgov_site/themes/custom/ncids_trans/templates/content/biography/field--field-title.html.twig
+++ b/docroot/profiles/custom/cgov_site/themes/custom/ncids_trans/templates/content/biography/field--field-title.html.twig
@@ -1,5 +1,5 @@
-<div class="profile-titles">
+<ul class="cgdp-profile-box__titles">
   {% for item in items %}
-    <div class="profile-title">{{ item.content }}</div>
+    <li class="cgdp-profile-box__title">{{ item.content }}</li>
   {% endfor %}
-</div>
+</ul>
diff --git a/docroot/profiles/custom/cgov_site/themes/custom/ncids_trans/templates/content/biography/field--field-twitter-handle.html.twig b/docroot/profiles/custom/cgov_site/themes/custom/ncids_trans/templates/content/biography/field--field-twitter-handle.html.twig
index 82d51672ea..8ab0dea99f 100644
--- a/docroot/profiles/custom/cgov_site/themes/custom/ncids_trans/templates/content/biography/field--field-twitter-handle.html.twig
+++ b/docroot/profiles/custom/cgov_site/themes/custom/ncids_trans/templates/content/biography/field--field-twitter-handle.html.twig
@@ -1,6 +1,6 @@
 {% for item in items %}
-    <a href="http://www.twitter.com/{{- item.content -}}" class="profile-social-link twitter no-exit-notification">
-        <i class="icon" aria-hidden="true"></i>
-        <span class="show-for-sr">Follow me on X</span>
-    </a>
-{% endfor %}
\ No newline at end of file
+  <a href="http://www.twitter.com/{{- item.content -}}" class="cgdp-profile-box__twitter no-exit-notification">
+    <i class="icon" aria-hidden="true"></i>
+    <span class="show-for-sr">Follow me on X</span>
+  </a>
+{% endfor %}
diff --git a/docroot/profiles/custom/cgov_site/themes/custom/ncids_trans/templates/content/biography/node--cgov-biography--full.html.twig b/docroot/profiles/custom/cgov_site/themes/custom/ncids_trans/templates/content/biography/node--cgov-biography--full.html.twig
index e020dbddb7..08749eae0b 100644
--- a/docroot/profiles/custom/cgov_site/themes/custom/ncids_trans/templates/content/biography/node--cgov-biography--full.html.twig
+++ b/docroot/profiles/custom/cgov_site/themes/custom/ncids_trans/templates/content/biography/node--cgov-biography--full.html.twig
@@ -2,71 +2,68 @@
 {% import '@ncids_trans/content_page_macros.twig' as contentPageMacros %}
 <!-- ********************************* BEGIN Page Content ********************************** -->
 <article>
-	<div class="cgdp-inner-content-area">
-		<div class="cgdpl">
-			<div class="contentzone">
-				<div id="nvcgSlProfilePanel" class="profile-panel">
-					<div class="slot-item only-SI">
-						<div class="profile-panel-image">
-							{{ content.field_image_promotional }}
-						</div>
-						<div class="profile-panel-content">
-							<h1>
-								{{ node.label }}
-							</h1>
+  <div class="cgdp-profile-box">
+    <div class="grid-row grid-gap">
+      <div class="tablet:grid-col-4">
+        {{ content.field_image_promotional }}
+      </div>
+      <div class="tablet:grid-col-8">
+        <h1 class="cgdp-profile-box__heading">{{ node.label }}</h1>
 
-							{{ content.field_title }}
+        <div class="cgdp-profile-box__field">
+          {{ content.field_title }}
 
-							{% if content.field_org_name_1|field_value or content.field_org_name_2|field_value %}
-								<div class="profile-orgs">
-									<div class="profile-org">
-										{% if content.field_org_url_1|field_value %}
-											<a href="{{- content.field_org_url_1|field_value -}}">{{ content.field_org_name_1 }}</a>
-										{% else %}
-											{{ content.field_org_name_1 }}
-										{% endif %}
-									</div>
+          {% if content.field_org_name_1|field_value or content.field_org_name_2|field_value %}
+            <ul class="cgdp-profile-box__org">
+              {% if content.field_org_url_1|field_value %}
+                <li><a href="{{- content.field_org_url_1|field_value -}}">{{ content.field_org_name_1 }}</a></li>
+              {% else %}
+                <li>{{ content.field_org_name_1 }}</li>
+              {% endif %}
 
-									{% if content.field_org_name_2|field_value %}
-										<div class="profile-org">
-											{% if content.field_org_url_2|field_value %}
-												<a href="{{- content.field_org_url_2|field_value -}}">{{ content.field_org_name_2 }}</a>
-											{% else %}
-												{{ content.field_org_name_2 }}
-											{% endif %}
-										</div>
-									{% endif %}
-								</div>
-							{% endif %}
+              {% if content.field_org_name_2|field_value %}
+                {% if content.field_org_url_2|field_value %}
+                  <li><a href="{{- content.field_org_url_2|field_value -}}">{{ content.field_org_name_2 }}</a></li>
+                {% else %}
+                  <li>{{ content.field_org_name_2 }}</li>
+                {% endif %}
+              {% endif %}
+            </ul>
+          {% endif %}
 
-							{% if content.field_campus|field_value or content.field_office_location|field_value %}
-								<p>
-									{{ content.field_campus }}
-									{{ (content.field_campus|field_value and content.field_office_location|field_value)? '|' : '' }}
-									{{ content.field_office_location }}
-								</p>
-							{% endif %}
+          <div class="cgdp-profile-box__address">
+            {% if content.field_campus|field_value or content.field_office_location|field_value %}
+              {{ content.field_campus }}
+              {{ (content.field_campus|field_value and content.field_office_location|field_value)? '|' : '' }}
+              {{ content.field_office_location }}
+            {% endif %}
+          </div>
 
-							{% if content.field_phone_number|field_value or content.field_email_address|field_value %}
-								<div class="profile-contact-info">
-									{{ content.field_phone_number}}
-									{{ (content.field_phone_number|field_value and content.field_email_address|field_value)? '<span class="contact-divider">|</span>': '' }}
-									{{ content.field_email_address }}
-								</div>
-							{% endif %}
+          <div class="cgdp-profile-box__phone">
+            {% if content.field_phone_number|field_value or content.field_email_address|field_value %}
+              {{ content.field_phone_number }}
+              {{ (content.field_phone_number|field_value and content.field_email_address|field_value)? '<span class="contact-divider">|</span>': '' }}
+              {{ content.field_email_address }}
+            {% endif %}
+          </div>
 
-							{% if content.field_twitter_handle|field_value or content.field_linkedin_handle|field_value or content.field_scientific_publications|field_value %}
-								<div class="profile-panel-social-media">
-									{{ content.field_twitter_handle }}
-									{{ content.field_linkedin_handle }}
-									{{ content.field_scientific_publications }}
-								</div>
-							{% endif %}
-						</div>
-					</div>
-				</div>
-				<!-- End profile-panel -->
+          {{ content.field_scientific_publications }}
 
+          <div class="cgdp-profile-box__social-media">
+            {% if content.field_twitter_handle|field_value or content.field_linkedin_handle|field_value or content.field_scientific_publications|field_value %}
+              {{ content.field_twitter_handle }}
+              {{ content.field_linkedin_handle }}
+            {% endif %}
+          </div>
+        </div>
+      </div>
+    </div>
+  </div>
+  <!-- End profile-panel -->
+
+	<div class="cgdp-inner-content-area">
+		<div class="cgdpl">
+			<div class="contentzone">
 				<div id="cgvBody">
 					{{ content.body }}
 					{% if node.field_display_bio_press_info.value == '1' %}
diff --git a/docroot/profiles/custom/cgov_site/themes/custom/ncids_trans/templates/content/cancer_center/address-plain.html.twig b/docroot/profiles/custom/cgov_site/themes/custom/ncids_trans/templates/content/cancer_center/address-plain.html.twig
index 116901ffcc..78057cae03 100644
--- a/docroot/profiles/custom/cgov_site/themes/custom/ncids_trans/templates/content/cancer_center/address-plain.html.twig
+++ b/docroot/profiles/custom/cgov_site/themes/custom/ncids_trans/templates/content/cancer_center/address-plain.html.twig
@@ -32,7 +32,7 @@
  * @ingroup themeable
  */
 #}
-<p class="address" translate="no">
+<div translate="no">
   {% if address_line1 %}
     {{ address_line1 }} <br>
   {% endif %}
@@ -55,4 +55,4 @@
       {{ postal_code }}
     {% endif %}
   {% endif %}
-</p>
+</div>
diff --git a/docroot/profiles/custom/cgov_site/themes/custom/ncids_trans/templates/content/cancer_center/node--cgov-cancer-center--full.html.twig b/docroot/profiles/custom/cgov_site/themes/custom/ncids_trans/templates/content/cancer_center/node--cgov-cancer-center--full.html.twig
index e6ac294669..52c2bbd663 100644
--- a/docroot/profiles/custom/cgov_site/themes/custom/ncids_trans/templates/content/cancer_center/node--cgov-cancer-center--full.html.twig
+++ b/docroot/profiles/custom/cgov_site/themes/custom/ncids_trans/templates/content/cancer_center/node--cgov-cancer-center--full.html.twig
@@ -2,64 +2,68 @@
 {% import '@ncids_trans/content_page_macros.twig' as contentPageMacros %}
 <!-- ********************************* BEGIN Page Content ********************************** -->
 <article>
-	<div class="cgdp-inner-content-area">
-		<div class="cgdpl">
-			<div class="contentzone">
-				<div id="nvcgSlProfilePanel" class="profile-panel">
-					<div
-						class="slot-item only-SI">
-						<!-- start profile panel content -->
-						<div class="profile-panel-image">
-							{{ content.field_image_promotional }}
-						</div>
-						<div class="profile-panel-content">
-							<h1>{{ node.label }}</h1>
-							{% if content.field_parent_institution[0] or content.field_institution_type[0] %}
-								<div class="profile-title">
-									{{ content.field_parent_institution }}
-									{% if content.field_parent_institution[0] and content.field_institution_type[0] %}
-										<br/>
-									{% endif %}
-									{{ content.field_institution_type }}
-								</div>
-							{%- endif -%}
-							{%- if content.field_org_head_name[0] -%}
-								<p>
-									{{ content.field_org_head_name|field_value }}
-									{%- if content.field_org_head_title[0] -%}
-										,
-										{{ content.field_org_head_title }}
-									{%- endif -%}
-								</p>
-							{%- endif -%}
+  <div class="cgdp-profile-box">
+    <div class="grid-row grid-gap">
+      <div class="tablet:grid-col-4">
+        {{ content.field_image_promotional }}
+      </div>
 
-							{% if content.field_address[0] %}
-								{{ content.field_address }}
-							{% endif %}
+      <div class="tablet:grid-col-8">
+        <h1 class="cgdp-profile-box__heading">{{ node.label }}</h1>
 
-							{% if content.field_phone_number_1[0] or content.field_phone_number_2[0]%}
-								<p>
-									{% if content.field_phone_label_1[0] and content.field_phone_number_1[0] %}
-										{{- content.field_phone_label_1|field_value -}}:
-										<a href="tel:{{- content.field_phone_number_1|field_value -}}" rel="nofollow">{{ content.field_phone_number_1 }}</a><br/>
-									{% endif %}
-									{% if content.field_phone_label_2[0] and content.field_phone_number_2[0] %}
-										{{ content.field_phone_label_2|field_value -}}:
-										<a href="tel:{{- content.field_phone_number_2|field_value -}}" rel="nofollow">{{ content.field_phone_number_2 }}</a>
-									{% endif %}
-								</p>
-							{% endif %}
+        <div class="cgdp-profile-box__field">
+          {% if content.field_parent_institution[0] or content.field_institution_type[0] %}
+            <ul class="cgdp-profile-box__titles">
+              {%- if content.field_parent_institution[0] -%}
+                <li class="cgdp-profile-box__title">{{ content.field_parent_institution }}</li>
+              {%- endif -%}
+              {%- if content.field_institution_type[0] -%}
+                <li class="cgdp-profile-box__title">{{ content.field_institution_type }}</li>
+              {%- endif -%}
+            </ul>
+          {%- endif -%}
 
-							{% if content.field_website_title[0] and content.field_website_url[0] %}
-								<p>
-									<a href="{{- content.field_website_url|field_value -}}">{{ content.field_website_title }}</a>
-								</p>
-							{% endif %}
-						</div>
-						<!-- end profile panel content -->
-					</div>
-				</div>
-				<!-- END Profile Panel slot -->
+          <div class="cgdp-profile-box__address">
+            {%- if content.field_org_head_name[0] -%}
+                {{ content.field_org_head_name|field_value }}
+                {%- if content.field_org_head_title[0] -%}
+                  ,
+                  {{ content.field_org_head_title }}
+                {%- endif -%}
+            {%- endif -%}
+
+            {% if content.field_address[0] %}
+              {{ content.field_address }}
+            {% endif %}
+
+            {% if content.field_phone_number_1[0] or content.field_phone_number_2[0] %}
+              <div>
+                {% if content.field_phone_label_1[0] and content.field_phone_number_1[0] %}
+                  {{- content.field_phone_label_1|field_value -}}:
+                  <a href="tel:{{- content.field_phone_number_1|field_value -}}" rel="nofollow">{{ content.field_phone_number_1 }}</a><br/>
+                {% endif %}
+                {% if content.field_phone_label_2[0] and content.field_phone_number_2[0] %}
+                  {{ content.field_phone_label_2|field_value -}}:
+                  <a href="tel:{{- content.field_phone_number_2|field_value -}}" rel="nofollow">{{ content.field_phone_number_2 }}</a>
+                {% endif %}
+              </div>
+            {% endif %}
+          </div>
+
+          {% if content.field_website_title[0] and content.field_website_url[0] %}
+            <div class="cgdp-profile-box__website">
+              <a href="{{- content.field_website_url|field_value -}}">{{ content.field_website_title }}</a>
+            </div>
+          {% endif %}
+        </div>
+      </div>
+    </div>
+  </div>
+  <!-- END Profile Panel slot -->
+
+	<div class="cgdp-inner-content-area">
+		<div class="cgdpl">
+			<div class="contentzone">
 				<div id="cgvBody">
 					{{ content.body }}
 				</div>