From 7db8886da24a3cb0b66174e3714364c402a80d76 Mon Sep 17 00:00:00 2001 From: "yi.hsiao" Date: Mon, 11 Nov 2024 00:58:34 -0500 Subject: [PATCH] update imputation page --- docs/documentation/imputation.md | 15 ++++----------- 1 file changed, 4 insertions(+), 11 deletions(-) diff --git a/docs/documentation/imputation.md b/docs/documentation/imputation.md index 43f73ef..1975f29 100644 --- a/docs/documentation/imputation.md +++ b/docs/documentation/imputation.md @@ -1,15 +1,8 @@ # Missing value imputation options -Multiple imputation options were provided in FragPipe-Analyst +Multiple imputation options were provided in FragPipe-Analyst. Perseus-style ** is applied by default for DDA and DIA LFQ data. No imputation is performed for TMT data by default. -- **Perseus-type:** This method is based on popular missing value - imputation procedure implemented in *Perseus* software by MaxQuant - team. The missing values are replaced by random numbers drawn from a - normal distribution of *1.8* standard deviation down shift and with a - width of *0.3* of each sample. -- **bpca:** Bayesian missing value imputation -- **knn:** Missing values replace by nearest neighbor averaging - technique -- **min:** Replaces the missing values by the smallest non-missing - value in the data. +- **Perseus-style**: This method is based on popular missing value imputation procedure implemented in *Perseus* software by MaxQuant team. The missing values are replaced by random numbers drawn from a normal distribution of *1.8* standard deviation down shift and with a width of *0.3* of each sample. +- **knn:** Missing values replace by nearest neighbor averaging technique +- **min:** Replaces the missing values by the smallest non-missing value in the data. - **zero:** Replaces the missing values by **0**.