diff --git a/requirements-bootstrap.txt b/requirements-bootstrap.txt
index 3af452a8d..f5d37f7a3 100644
--- a/requirements-bootstrap.txt
+++ b/requirements-bootstrap.txt
@@ -1,5 +1,5 @@
 pip==18.1
-setuptools==49.2.1
+setuptools==65.5.1
 venv-update==3.2.4
 virtualenv==20.6.0
 wheel==0.32.3
diff --git a/requirements.txt b/requirements.txt
index e3f09a3e1..3ef045ff4 100644
--- a/requirements.txt
+++ b/requirements.txt
@@ -40,7 +40,7 @@ retry==0.9.2
 rsa==4.6
 s3transfer==0.3.2
 semver==2.13.0
-setuptools==49.2.1
+setuptools==65.5.1
 signalfx==1.1.1
 simplejson==3.16.0
 six==1.15.0