diff --git a/src/clients/MultiCallerClient.ts b/src/clients/MultiCallerClient.ts
index 7f2ba00ec..033e93ec8 100644
--- a/src/clients/MultiCallerClient.ts
+++ b/src/clients/MultiCallerClient.ts
@@ -16,6 +16,7 @@ import {
   getProvider,
   Multicall2Call,
   assert,
+  getPermissionedMultisender,
 } from "../utils";
 import { AugmentedTransaction, TransactionClient } from "./TransactionClient";
 import lodash from "lodash";
@@ -260,10 +261,21 @@ export class MultiCallerClient {
     return this.baseSigner ? getMultisender(chainId, this.baseSigner.connect(await getProvider(chainId))) : undefined;
   }
 
+  async _getPermissionedMultisender(chainId: number): Promise<Contract | undefined> {
+    return this.baseSigner
+      ? getPermissionedMultisender(chainId, this.baseSigner.connect(await getProvider(chainId)))
+      : undefined;
+  }
+
   async buildMultiSenderBundle(transactions: AugmentedTransaction[]): Promise<AugmentedTransaction> {
     // Validate all transactions have the same chainId and can be sent from multisender.
     const { chainId } = transactions[0];
-    const multisender = await this._getMultisender(chainId);
+    // If any transactions are to be sent through the permissioned multisender, then we should use that instead
+    // of the default multisender. This means that the caller must only batch transactions to this chain that can
+    // be executed from the permissioned multisender.
+    const multisender = transactions.some((t) => t.sendThroughPermissionedMulticall)
+      ? await this._getPermissionedMultisender(chainId)
+      : await this._getMultisender(chainId);
     if (!multisender) {
       throw new Error("Multisender not available for this chain");
     }
@@ -272,12 +284,17 @@ export class MultiCallerClient {
     const callData: Multicall2Call[] = [];
     let gasLimit: BigNumber | undefined = bnZero;
     transactions.forEach((txn, idx) => {
-      if (!txn.unpermissioned || txn.chainId !== chainId) {
+      if (!txn.unpermissioned || !txn.sendThroughPermissionedMulticall || txn.chainId !== chainId) {
         this.logger.error({
           at: "MultiCallerClient#buildMultiSenderBundle",
           message: "Some transactions in the queue contain different target chain or are permissioned",
           transactions: transactions.map(({ contract, chainId, unpermissioned }) => {
-            return { target: getTarget(contract.address), unpermissioned: Boolean(unpermissioned), chainId };
+            return {
+              target: getTarget(contract.address),
+              unpermissioned: Boolean(unpermissioned),
+              sendThroughPermissionedMulticall: Boolean(txn.sendThroughPermissionedMulticall),
+              chainId,
+            };
           }),
           notificationPath: "across-error",
         });
@@ -380,7 +397,7 @@ export class MultiCallerClient {
       multisenderTxns = [],
       unsendableTxns = [],
     } = lodash.groupBy(txns, (txn) => {
-      if (txn.unpermissioned) {
+      if (txn.unpermissioned || txn.sendThroughPermissionedMulticall) {
         return "multisenderTxns";
       } else if (txn.contract.multicall) {
         return "multicallerTxns";
diff --git a/src/clients/TransactionClient.ts b/src/clients/TransactionClient.ts
index 84a1e092d..50c08ca79 100644
--- a/src/clients/TransactionClient.ts
+++ b/src/clients/TransactionClient.ts
@@ -26,6 +26,8 @@ export interface AugmentedTransaction {
   value?: BigNumber;
   unpermissioned?: boolean; // If false, the transaction must be sent from the enqueuer of the method.
   // If true, then can be sent from the MakerDAO multisender contract.
+  sendThroughPermissionedMulticall?: boolean;
+  // If true, then should be sent through the permissioned multisender contract.
   canFailInSimulation?: boolean;
   // Optional batch ID to use to group transactions
   groupId?: string;
diff --git a/src/finalizer/index.ts b/src/finalizer/index.ts
index 296afdc34..49a265075 100644
--- a/src/finalizer/index.ts
+++ b/src/finalizer/index.ts
@@ -294,8 +294,8 @@ export async function finalize(
         hubChainId,
         ...configuredChainIds,
       ]).map(
-        async (chainId) =>
-          [chainId, await getMultisender(chainId, spokePoolClients[chainId].spokePool.signer)] as [number, Contract]
+        (chainId) =>
+          [chainId, getMultisender(chainId, spokePoolClients[chainId].spokePool.signer)] as [number, Contract]
       )
     )
   );
diff --git a/src/utils/TransactionUtils.ts b/src/utils/TransactionUtils.ts
index a0bb308b4..56b16a72a 100644
--- a/src/utils/TransactionUtils.ts
+++ b/src/utils/TransactionUtils.ts
@@ -53,10 +53,14 @@ export function getNetworkError(err: unknown): string {
   return isEthersError(err) ? err.reason : isError(err) ? err.message : "unknown error";
 }
 
-export async function getMultisender(chainId: number, baseSigner: Signer): Promise<Contract | undefined> {
+export function getMultisender(chainId: number, baseSigner: Signer): Contract | undefined {
   return sdkUtils.getMulticall3(chainId, baseSigner);
 }
 
+export function getPermissionedMultisender(chainId: number, baseSigner: Signer): Contract | undefined {
+  return sdkUtils.getPermissionedMulticall3(chainId, baseSigner);
+}
+
 // Note that this function will throw if the call to the contract on method for given args reverts. Implementers
 // of this method should be considerate of this and catch the response to deal with the error accordingly.
 export async function runTransaction(