diff --git a/README.md b/README.md
index 41d8b3b..e73720b 100644
--- a/README.md
+++ b/README.md
@@ -19,10 +19,10 @@ tmux
 
 # Shortcuts
 
-* `Ctrl + a, Ctrl + c` or `Ctrl + t`: create a new window
-* `Ctrl + a, Ctrl + s`: create a new nested tmux session and ask a name for it
-* `Ctrl + a, Ctrl + A`: switch to last window
-* `Ctrl + a, A`: rename current window
+* `Ctrl + z, Ctrl + c` or `Ctrl + t`: create a new window
+* `Ctrl + z, Ctrl + s`: create a new nested tmux session and ask a name for it
+* `Ctrl + z, Ctrl + A`: switch to last window
+* `Ctrl + z, A`: rename current window
 * `Alt + Right`: move to the next window of the current row
 * `Alt + Left`: move to the previous window of the current row
 * `Alt + Up`: move to the inner tmux session
diff --git a/active-row.conf b/active-row.conf
index ac89b0c..bdf3c76 100644
--- a/active-row.conf
+++ b/active-row.conf
@@ -18,24 +18,28 @@ set -g history-limit 100000
 # Configure prefix
 #
 unbind C-b
-set -g prefix C-a
+# Avoid clobbering common readline bindings which should be very fast, whereas
+# backgrounding a process is relatively incommon and the double-prefix is fine.
+set -g prefix C-z
+# Pass the prefix through (Ctrl + z, Ctrl + z)
+bind C-z send-prefix
 
 #
 # Prefixed commands
 #
 
-# Create a new window (Ctrl + A, Ctrl + c)
+# Create a new window (Ctrl + z, Ctrl + c)
 bind C-c new-window
 
-# Create a new nested tmux (Ctrl + A, Ctrl + s)
+# Create a new nested tmux (Ctrl + z, Ctrl + s)
 bind C-s new-window ~/.tmux.conf.d/nested-tmux/new-tmux \; \
          rename-window '' \; \
          command-prompt -I "#W" "rename-window -- '%%'"
 
-# Switch to last window (Ctrl + A, Ctrl + A)
-bind C-a last-window
+# Switch to last window (Ctrl + z, Ctrl + e)
+bind C-e last-window
 
-# Rename current window (Ctrl + A, A)
+# Rename current window (Ctrl + z, A)
 bind A  rename-window '' \; \
         command-prompt -I "#W" "rename-window -- '%%'"
 
@@ -52,9 +56,6 @@ bind -n M-right next
 # Go to previous window (Alt + Left)
 bind -n M-left  prev
 
-# Create new window (Ctrl + t)
-bind -n C-t new-window
-
 # Switch to inner tmux (Alt + Up)
 bind -n M-up send-keys M-F12
 
diff --git a/inactive-row.conf b/inactive-row.conf
index 9386468..e545dde 100644
--- a/inactive-row.conf
+++ b/inactive-row.conf
@@ -2,7 +2,7 @@
 setw -g window-status-current-style bg=$inactive_window_bg
 
 # Unbind prefix
-set -u -g prefix C-a
+set -u -g prefix C-z
 
 # Unbind each unprefixed command
 unbind -n M-left