diff --git a/app/README.md b/app/README.md index db65eb8c..0935616b 100644 --- a/app/README.md +++ b/app/README.md @@ -1,3 +1,4 @@ + # App The app displays user-specific [PGx](../docs/GLOSSARY.md) information. @@ -6,15 +7,15 @@ Once the user imports their genomic data into the app, [PGx](../docs/GLOSSARY.md) guidelines matching the user's genetic profile are displayed. -Users can review their gene results [(a), (b)], search for drugs (c), and receive -information about whether a drug can be used at standard dose or if the -treatment may need to be changed (d). +Users can review their gene results [(a), (b)], search for medications (c), and +receive information about whether a medication can be used at standard dose or +if the treatment may need to be changed (d). -Anytreatment changes should be approved by a pharmacist or physician as well. +Any treatment changes should be approved by a pharmacist or physician as well. To inform the physician of the [PGx](../docs/GLOSSARY.md) results, the application offers to export a detailed description. -PGx report | Gene details | Drug search | Drug details | +PGx report | Gene details | Medication search | Medication details | :-: | :-: | :-: | :-: | (a) | (b) | (c) | (d) | ![report_screen](../docs/screenshots/gene-report.png) | ![gene_screen](../docs/screenshots/cyp2d6.png) | ![search_screen](../docs/screenshots/drug-search.png) | ![drug_screen](../docs/screenshots/clopidogrel.png) | diff --git a/app/lib/faq/constants.dart b/app/lib/faq/constants.dart index f33f33dc..026cc563 100644 --- a/app/lib/faq/constants.dart +++ b/app/lib/faq/constants.dart @@ -29,12 +29,12 @@ final Map> faqList = { TextAnswerQuestion( question: 'What is pharmacogenomics?', answer: - 'Pharmacogenomics (PGx) is the study of how your genes (DNA) affect your response to drugs.', + 'Pharmacogenomics (PGx) is the study of how your genes (DNA) affect your response to medications.', ), TextAnswerQuestion( question: 'Why is pharmacogenomics important?', answer: - 'Pharmacogenomics is important because it helps to predict those who will respond well to drugs and those who may have side effects. With this information we can better select the right drug and dose to avoid side effects.', + 'Pharmacogenomics is important because it helps to predict those who will respond well to medications and those who may have side effects. With this information we can better select the right medication and dose to avoid side effects.', ), WidgetAnswerQuestion( question: 'Where can I find out more about genetics in general?', @@ -54,9 +54,9 @@ final Map> faqList = { ), ), TextAnswerQuestion( - question: 'Which drugs are affected?', + question: 'Which medications are affected?', answer: - 'Examples of affected drug classes include anti-clotting medications (like clopidogrel and warfarin), antidepressants (like sertraline, citalopram, and paroxetine), anti-cholesterol drugs (like simvastatin and atorvastatin), acid reducers (like pantoprazole and omeprazole), pain killers (like codeine, tramadol, and ibuprofen), antifungals (like voriconazole), drugs that suppress the immune system (like tacrolimus), and anti-cancer drugs (like fluorouracil and irinotecan). You can find out whether a certain drug is affected in the Search tab.', + 'Examples of affected medication classes include anti-clotting medications (like clopidogrel and warfarin), antidepressants (like sertraline, citalopram, and paroxetine), anti-cholesterol medications (like simvastatin and atorvastatin), acid reducers (like pantoprazole and omeprazole), pain killers (like codeine, tramadol, and ibuprofen), antifungals (like voriconazole), medications that suppress the immune system (like tacrolimus), and anti-cancer medications (like fluorouracil and irinotecan). You can find out whether a certain medication is affected in the Medications tab.', ), TextAnswerQuestion( question: 'Will my results affect my family members?', @@ -73,13 +73,13 @@ final Map> faqList = { TextAnswerQuestion( question: 'What does PharMe do?', answer: - 'PharMe provides user-friendly information on how your body reacts to drugs based on your genes. This enables you to better understand which drugs may be ineffective for you or could have potential side effects. We recommend that you share consult your health care team before making any changes to your treatments.', + 'PharMe provides user-friendly information on how your body reacts to medications based on your genes. This enables you to better understand which medications may be ineffective for you or could have potential side effects. We recommend that you share consult your health care team before making any changes to your treatments.', ), TextAnswerQuestion( question: 'Can I use PharMe\'s results without consulting a medical professional?', answer: - 'No. Whether a drug is a good choice for you depends on a lot of other factors such as age, weight, or pre-existing conditions. We highly recommend that you talk to your health care team (e.g., pharmacist and doctors) before taking, stopping or adjusting the dose of any drug.', + 'No. Whether a medication is a good choice for you depends on a lot of other factors such as age, weight, or pre-existing conditions. We highly recommend that you talk to your health care team (e.g., pharmacist and doctors) before taking, stopping or adjusting the dose of any medication.', ), TextAnswerQuestion( question: 'Where does PharMe get its data from?', diff --git a/docs/GLOSSARY.md b/docs/GLOSSARY.md index 97add3b2..57b36788 100644 --- a/docs/GLOSSARY.md +++ b/docs/GLOSSARY.md @@ -74,28 +74,29 @@ understanding of this project's code. individual that has one CYP2D6 star one variant from one parent and one star two variant from the other. -s + ## Terms used in our projects
Implication
-
For a given drug-phenotype pair, an implication describes what - effects the phenotype has on use of the drug. An example for an +
For a given medication-phenotype pair, an implication describes what + effects the phenotype has on use of the medication. An example for an implication is "Increased risk of side effects".
Recommendation
-
For a given drug-phenotype pair, a recommendation describes what an +
For a given medication-phenotype pair, a recommendation describes what an individual should do based on the corresponding implication, e.g. "Use a lower dose".
Guideline
Consists of the implication and recommendation for a given - drug-phenotype pair.
+ medication-phenotype pair.
Annotation
Describes data that is manually curated for our project, i.e. implication - and recommendation for a drug-phenotype pair and indication, a - patient-friendly drug-class, and common brand names for a drug.
+ and recommendation for a medication-phenotype pair and indication, a + patient-friendly medication class, and common brand names for a + medication.
(Text) Brick
*Text Bricks* are predefined components that are used to create texts for @@ -103,5 +104,5 @@ s combinations of Bricks to ensure consistency and enable easy multi-language support without the need of the maintainer having to know more than one supported language. Bricks can also include placeholders such as a given - drug's name
+ medication's name
diff --git a/pharme.code-workspace b/pharme.code-workspace index dfe73d11..5ddc105f 100644 --- a/pharme.code-workspace +++ b/pharme.code-workspace @@ -34,27 +34,39 @@ "cSpell.words": [ "abiraterone", "anni", + "atorvastatin", "bupropion", "cinacalcet", + "citalopram", "clopidogrel", "CPIC", "diplotype", "diplotypes", "drugclass", "duloxetine", + "fluorouracil", "haplotype", "haplotypes", "Hasso", + "irinotecan", "Keycloak", "MedlinePlus", "Metabolizer", + "omeprazole", + "pantoprazole", + "paroxetine", "pharmacogenetics", "Pharmacogenetics", "pharmacogenomic", "pharmacogenomics", "PharMe", "phenoconversion", - "Plattner" + "Plattner", + "sertraline", + "simvastatin", + "tacrolimus", + "tramadol", + "voriconazole" ] } }