I've kind of witnessed this already. Essentially when the KinectController emulates keyboard events, only some programs will actually accept the event and process it. This is because Windows sends these events to applications and it's completely up to these applications whether they want to accept that input or not.
This potentially is going to bring rise to a list of unsupported applications. The KinectController is going to suffer a fatal blow when the users find out that they can't use it to play their favorite video game. All we can really do is try to do what we can with the bad applications -- which might include skyrim -- and try to attain the maximum level of support possible.