diff --git a/DESCRIPTION b/DESCRIPTION
index 748d00d..38ebad3 100644
--- a/DESCRIPTION
+++ b/DESCRIPTION
@@ -9,7 +9,7 @@ Authors@R: c(
                  comment = c(ORCID = "0000-0002-1386-0435")))
 Description: Genome Association and Prediction Integrated Tools.
 License: GPL (>= 2)
-Depends: R (>= 4.1.2)
+Depends: R (<= 4.4.1)
 biocViews:
 Imports:
     ape,
diff --git a/README.md b/README.md
index ab69195..85c4ca8 100644
--- a/README.md
+++ b/README.md
@@ -122,7 +122,15 @@ R> library(GAPIT)
 
 
 ```
+### In some case of the BiocManager can not be installed
 
+Installation of same packages such as multtest and biobase can not be intalled from BiocManager. These packages can be downloaded in the Bioconductor website and be installed from local source files.
+
+The website of Bioconductor is here:
+
+```
+https://bioconductor.org/packages/3.19/bioc/
+```
 
 ### Installation from an archive