NanoString nCounter is a medium-throughput platform that measures gene or microRNA expression levels. Here is a publication that introduces this platform: Malkov (2009) doi:10.1186/1756-0500-2-80. Here is the webpage of NanoString nCounter where you can find detailed information about this platform https://www.nanostring.com/scientific-content/technology-overview/ncounter-technology. It has great clinical application, such as diagnosis and prognosis of cancer. This R package implements integrated system of random-coefficient hierarchical regression model to normalize data from NanoString nCounter platform so that noise from various sources can be removed.