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DeepUMQA

Ultrafast Shape Recognition-based Protein Model Quality Assessment using Deep Learning

Developer:

        Saisai Guo and Jun Liu
        College of Information Engineering
        Zhejiang University of Technology, Hangzhou 310023, China
        Email: [email protected], [email protected]

Contact:

        Guijun Zhang, Prof
        College of Information Engineering
        Zhejiang University of Technology, Hangzhou 310023, China
        Email: [email protected]

INSTALLATION

  • Python > 3.5
  • PyTorch 1.3
  • PyRosetta
  • Tested on Ubuntu 20.04 LTS

RUNNING

DeepUMQA.py 

arguments:
  input                 path to input
  output                path to output (folder path, npz, or csv)

optional arguments:
  -h, --help            show this help message and exit
  --pdb, -pdb           Running on a single pdb 
  --csv, -csv           Writing results to a csv file 
  --per_res_only, -pr   Writing per-residue accuracy only 
  --leaveTempFile, -lt  Leaving temporary files 
  --process PROCESS, -p PROCESS
                       
  --featurize, -f       Running only the featurization part 
  --reprocess, -r       Reprocessing all feature files 
  --verbose, -v         Activating verbose flag 
  --ensemble, -e        Running with ensembling of 4 models. 
                   
  1. Predicting

         # Running on a folder of pdbs
         
         python DeepUMQA.py -r -v input/ output/
    
         # Running on a single pdb file
    
         python DeepUMQA.py -r -v --pdb pdbfile
    
  2. Feature extracting

python DeepUMQA.py --featurize input/ outputFea/

  1. Traning

python train.py models/

DISCLAIMER

The executable software and the source code of DeepUMQA is distributed free of charge as it is to any non-commercial users. The authors hold no liabilities to the performance of the program.

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DeepUMQA: Ultrafast Shape Recognition-based Protein Model Quality Assessment using Deep Learning

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