diff --git a/changes/5868.fix.md b/changes/5868.fix.md
new file mode 100644
index 00000000000..d9d57954db4
--- /dev/null
+++ b/changes/5868.fix.md
@@ -0,0 +1 @@
+Handle Storage Proxy connection error from Manager side
diff --git a/src/ai/backend/manager/clients/storage_proxy/manager_facing_client.py b/src/ai/backend/manager/clients/storage_proxy/manager_facing_client.py
index 9a9379ad019..54c8bfce1ad 100644
--- a/src/ai/backend/manager/clients/storage_proxy/manager_facing_client.py
+++ b/src/ai/backend/manager/clients/storage_proxy/manager_facing_client.py
@@ -33,7 +33,10 @@
 from ai.backend.manager.clients.storage_proxy.base import StorageProxyHTTPClient
 from ai.backend.manager.decorators.client_decorator import create_layer_aware_client_decorator
 from ai.backend.manager.defs import DEFAULT_CHUNK_SIZE
-from ai.backend.manager.errors.storage import UnexpectedStorageProxyResponseError
+from ai.backend.manager.errors.storage import (
+    StorageProxyConnectionError,
+    UnexpectedStorageProxyResponseError,
+)
 
 client_decorator = create_layer_aware_client_decorator(LayerType.STORAGE_PROXY_CLIENT)
 
@@ -57,7 +60,10 @@ async def get_volumes(self) -> Mapping[str, Any]:
 
         :return: Response containing volume information
         """
-        return await self._client.request_with_response("GET", "volumes")
+        try:
+            return await self._client.request_with_response("GET", "volumes")
+        except aiohttp.ClientConnectionError as e:
+            raise StorageProxyConnectionError from e
 
     @client_decorator()
     async def create_folder(
diff --git a/src/ai/backend/manager/clients/storage_proxy/session_manager.py b/src/ai/backend/manager/clients/storage_proxy/session_manager.py
index 7d23b9ceab2..29e46920c8c 100644
--- a/src/ai/backend/manager/clients/storage_proxy/session_manager.py
+++ b/src/ai/backend/manager/clients/storage_proxy/session_manager.py
@@ -28,6 +28,7 @@
 )
 from ai.backend.manager.config.unified import VolumesConfig
 from ai.backend.manager.errors.storage import (
+    StorageProxyConnectionError,
     StorageProxyNotFound,
 )
 
@@ -177,7 +178,11 @@ async def _fetch(
             proxy_name: str,
             client: StorageProxyManagerFacingClient,
         ) -> Iterable[tuple[str, VolumeInfo]]:
-            reply = await client.get_volumes()
+            try:
+                reply = await client.get_volumes()
+            except StorageProxyConnectionError:
+                log.warning("Failed to connect to storage proxy (name: {})", proxy_name)
+                return []
             return ((proxy_name, volume_data) for volume_data in reply["volumes"])
 
         for proxy_name, client in self._manager_facing_clients.items():
diff --git a/src/ai/backend/manager/errors/storage.py b/src/ai/backend/manager/errors/storage.py
index 5c235239bde..48e4ede7665 100644
--- a/src/ai/backend/manager/errors/storage.py
+++ b/src/ai/backend/manager/errors/storage.py
@@ -282,6 +282,19 @@ def error_code(cls) -> ErrorCode:
         )
 
 
+class StorageProxyConnectionError(BackendAIError, web.HTTPClientError):
+    error_type = "https://api.backend.ai/probs/storage-proxy-connection-error"
+    error_title = "Failed to connect to the storage proxy."
+
+    @classmethod
+    def error_code(cls) -> ErrorCode:
+        return ErrorCode(
+            domain=ErrorDomain.STORAGE_PROXY,
+            operation=ErrorOperation.REQUEST,
+            error_detail=ErrorDetail.UNREACHABLE,
+        )
+
+
 class UnexpectedStorageProxyResponseError(BackendAIError, web.HTTPInternalServerError):
     error_type = "https://api.backend.ai/probs/unexpected-storage-proxy-response"
     error_title = "Unexpected response from storage proxy."