The following key binding are good for dvorak layout:
(define-key key-translation-map [?\C-x] [?\C-u])
(define-key key-translation-map [?\C-u] [?\C-x])
(global-set-key (kbd "C-h") 'delete-backward-char)
(global-set-key (kbd "C-x C-h") 'execute-extended-command)
(global-set-key (kbd "C-x DEL") 'execute-extended-command)
But they makes me unable to use every instance of emacs that doesn't provide them :) so I decided to keep the standards.
gmime-2.6 xapian
autoreconf -i ./configure --prefix=$HOME/.emacs.d/mu make check make install