RUM data on some project I have suggested that "lite-youtube.lyt-activated>button.lty-playbtn" interaction is causing large INP.
I would suggest yielding on the Click Event Handler doing something similar to this and improve the UX somehow like changing the Playback icon status etc to improve UX on top of INP.
this.addEventListener('click', function(event) {
event.preventDefault();
requestAnimationFrame(() => {
setTimeout(() => {
if (this.classList.contains('lyt-activated')) return;
...