diff --git a/requirements/REQUIREMENTS-CI.txt b/requirements/REQUIREMENTS-CI.txt
index d5523e27..b5ac67b5 100644
--- a/requirements/REQUIREMENTS-CI.txt
+++ b/requirements/REQUIREMENTS-CI.txt
@@ -154,7 +154,7 @@ types-setuptools==80.3.0.20250505
 types-urllib3==1.26.25.14
 typing_extensions==4.13.2
 tzdata==2025.2
-urllib3==1.26.20
+urllib3==2.5.0
 validators==0.35.0
 wcwidth==0.2.13
 webencodings==0.5.1
diff --git a/requirements/REQUIREMENTS-JUPYTER.txt b/requirements/REQUIREMENTS-JUPYTER.txt
index 983e71af..89606de7 100644
--- a/requirements/REQUIREMENTS-JUPYTER.txt
+++ b/requirements/REQUIREMENTS-JUPYTER.txt
@@ -132,7 +132,7 @@ types-python-dateutil==2.9.0.20241206
 typing_extensions==4.12.2
 tzdata==2025.2
 uri-template==1.3.0
-urllib3==1.26.20
+urllib3==2.5.0
 validators==0.35.0
 wcwidth==0.2.13
 webcolors==24.11.1
diff --git a/requirements/REQUIREMENTS-NAPARI-CI.txt b/requirements/REQUIREMENTS-NAPARI-CI.txt
index 48e72bf5..91ef487b 100644
--- a/requirements/REQUIREMENTS-NAPARI-CI.txt
+++ b/requirements/REQUIREMENTS-NAPARI-CI.txt
@@ -151,7 +151,7 @@ triangle==20250106
 typer==0.15.2
 typing_extensions==4.12.2
 tzdata==2025.1
-urllib3==1.26.20
+urllib3==2.5.0
 validators==0.34.0
 vispy==0.14.3
 wcwidth==0.2.13
diff --git a/starfish/REQUIREMENTS-STRICT.txt b/starfish/REQUIREMENTS-STRICT.txt
index 245eb537..d9bb7bc5 100644
--- a/starfish/REQUIREMENTS-STRICT.txt
+++ b/starfish/REQUIREMENTS-STRICT.txt
@@ -51,7 +51,7 @@ tifffile==2024.8.30
 tqdm==4.67.1
 trackpy==0.6.4
 tzdata==2025.2
-urllib3==1.26.20
+urllib3==2.5.0
 validators==0.35.0
 xarray==2023.8.0
 zipp==3.21.0