circuits.jsonl

{"id": "bg_direct", "name": "Direct pathway (motor)", "structures": ["frontal_R", "frontal_L", "putamen_R", "putamen_L", "globus_pallidus_R", "globus_pallidus_L", "substantia_nigra_R", "substantia_nigra_L", "thalamus_R", "thalamus_L"], "description": "The movement-promoting basal-ganglia loop: cortex excites the striatum, which inhibits the GPi/SNr output, releasing the thalamus to drive cortex.", "sources": [{"quote_id": "q_50f31a69f353", "provenance": "verified"}], "wikipedia": "https://en.wikipedia.org/wiki/Direct_pathway", "wikipedia_provenance": "sourced", "structure_image": "https://upload.wikimedia.org/wikipedia/commons/1/15/Motor_loop.png"}
{"id": "bg_indirect", "name": "Indirect pathway", "structures": ["frontal_R", "frontal_L", "putamen_R", "putamen_L", "globus_pallidus_R", "globus_pallidus_L", "subthalamic_nucleus_R", "subthalamic_nucleus_L", "thalamus_R", "thalamus_L"], "description": "The movement-suppressing loop, routed through the subthalamic nucleus, which drives the GPi/SNr to clamp the thalamus.", "sources": [{"quote_id": "q_2e395cee718f", "provenance": "verified"}], "wikipedia": "https://en.wikipedia.org/wiki/Indirect_pathway", "wikipedia_provenance": "sourced", "structure_image": "https://upload.wikimedia.org/wikipedia/commons/1/15/Motor_loop.png"}
{"id": "nigrostriatal", "name": "Nigrostriatal (dopamine)", "structures": ["substantia_nigra_R", "substantia_nigra_L", "putamen_R", "putamen_L", "caudate_R", "caudate_L"], "description": "The dopaminergic projection from the substantia nigra to the striatum whose loss causes Parkinson's disease.", "sources": [{"quote_id": "q_6d2a1ac8fd34", "provenance": "verified"}], "wikipedia": "https://en.wikipedia.org/wiki/Nigrostriatal_pathway", "wikipedia_provenance": "sourced", "structure_image": "https://upload.wikimedia.org/wikipedia/commons/5/52/Nigrostriatal_pathway.svg", "structure_image_gallery": ["https://upload.wikimedia.org/wikipedia/commons/1/10/Basal_ganglia_diagram.svg"]}
{"id": "cerebellar_motor", "name": "Cortico-cerebellar (motor)", "structures": ["frontal_R", "frontal_L", "pons", "cerebellum", "thalamus_R", "thalamus_L"], "description": "The coordination loop: cortex to pons to cerebellum to thalamus and back, tuning the timing of movement.", "sources": [{"quote_id": "q_aec8781ec4ae", "provenance": "verified"}]}
{"id": "limbic_memory", "name": "Hippocampal / limbic (Papez)", "structures": ["temporal_R", "temporal_L", "hippocampus_R", "hippocampus_L", "fornix_R", "fornix_L", "mammillary_R", "mammillary_L", "thalamus_R", "thalamus_L", "cingulate_R", "cingulate_L"], "description": "The Papez circuit: the medial-temporal memory loop through hippocampus, fornix, mammillary bodies, anterior thalamus and cingulate.", "sources": [{"quote_id": "q_e0bb344a9423", "provenance": "verified"}], "wikipedia": "https://en.wikipedia.org/wiki/Papez_circuit", "wikipedia_provenance": "sourced", "structure_image": "https://upload.wikimedia.org/wikipedia/commons/6/65/Brain_limbicsystem.svg"}
{"id": "commissures", "name": "Commissures (interhemispheric)", "structures": ["frontal_R", "frontal_L", "parietal_R", "parietal_L", "temporal_R", "temporal_L", "occipital_R", "occipital_L"], "description": "The interhemispheric bridges (corpus callosum + anterior commissure) linking matching cortical areas across the midline.", "sources": [{"quote_id": "q_5368a2ae0717", "provenance": "verified"}], "wikipedia": "https://en.wikipedia.org/wiki/Commissural_fiber", "wikipedia_provenance": "sourced", "structure_image": "https://upload.wikimedia.org/wikipedia/commons/b/b4/Gray744.png"}