Hello,
Thank you so much for developing this tool. I testing in on some of our data and I would like to hear your thoughts in choosing the correct parameters for cnvkit and all various coral commands.
Out of the box, coral is designed to work with standard long reads. Would coral still perform reasonably well on DNA that is fragmented and/or short? For example, cell-free DNA is mostly 167bp long fragments. Are there any settings to tweak when working with this assumption?
Many thanks,
Alex
Hello,
Thank you so much for developing this tool. I testing in on some of our data and I would like to hear your thoughts in choosing the correct parameters for cnvkit and all various coral commands.
Out of the box, coral is designed to work with standard long reads. Would coral still perform reasonably well on DNA that is fragmented and/or short? For example, cell-free DNA is mostly 167bp long fragments. Are there any settings to tweak when working with this assumption?
Many thanks,
Alex