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# Missing value imputation options | ||
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Multiple imputation options were provided in FragPipe-Analyst | ||
Multiple imputation options were provided in FragPipe-Analyst. Perseus-style ** is applied by default for DDA and DIA LFQ data. No imputation is performed for TMT data by default. | ||
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- **Perseus-type:** This method is based on popular missing value | ||
imputation procedure implemented in *Perseus* software by MaxQuant | ||
team. The missing values are replaced by random numbers drawn from a | ||
normal distribution of *1.8* standard deviation down shift and with a | ||
width of *0.3* of each sample. | ||
- **bpca:** Bayesian missing value imputation | ||
- **knn:** Missing values replace by nearest neighbor averaging | ||
technique | ||
- **min:** Replaces the missing values by the smallest non-missing | ||
value in the data. | ||
- **Perseus-style**: This method is based on popular missing value imputation procedure implemented in *Perseus* software by MaxQuant team. The missing values are replaced by random numbers drawn from a normal distribution of *1.8* standard deviation down shift and with a width of *0.3* of each sample. | ||
- **knn:** Missing values replace by nearest neighbor averaging technique | ||
- **min:** Replaces the missing values by the smallest non-missing value in the data. | ||
- **zero:** Replaces the missing values by **0**. |