Create glyma.Acharya_Troelle_2024.yml

Glycine/max/studies/glyma.Acharya_Troelle_2024.yml

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+---
+scientific_name: Glycine max
+gene_symbols:
+  - GmPGIP11
+gene_symbol_long: Polygalacturonase Inhibiting Protein 11
+gene_model_pub_name: Glyma.19G145200
+gene_model_full_id: glyma.Wm82.gnm4.ann1.Glyma.19G145200
+confidence: 5
+curators:
+  - Molly Hardacre
+comments:
+  - GmPGIP11 is a polygalacturonase inhibiting protein in soybean roots that is
+    expressed during defense responses against the soybean cyst nematode,
+    Heterodera glycines. PGIP11 inhibits pathogen-secreted polygalacturonases
+    responsible for cell wall degradation.
+  - Overexpression of GmPGIP11 in soybean roots leads to increased transcript
+    abundance and significantly reduces Heterodera glycines parasitism without
+    adversely affecting soybean root growth, whereas RNA interference knockdown
+    of GmPGIP11 increases susceptibility to the nematode.
+  - The expression of GmPGIP11 is modulated by components of both PAMP-triggered
+    immunity and effector-triggered immunity signaling pathways.
+  - GmPGIP11 belongs to a small gene family with distinct expression patterns,
+    and unlike other PGIPs, it's specifically upregulated in syncytial nurse
+    cells during the defense response to nematode infection.
+  - PGIP family genes have been shown to play similar/important roles in plant
+    defense (specifically nematode defense) across various species. For example,
+    in Arabidopsis thaliana, AtPGIP1 increases in response to Heterodera
+    schachtii invasion. The loss-of-function mutants are more susceptible,
+    whereas overexpression of AtPGIP1 restores resistance.
+phenotype_synopsis: GmPGIP11 functions as a defense-related gene in soybean
+  roots, where its overexpression significantly reduces Heterodera glycines
+  parasitism without affecting root growth, while its suppression via RNA
+  interference increases susceptibility to the nematode.
+traits:
+  - entity_name: Heterodera glycines response
+    entity: TO:0001111
+  - entity_name: defense response
+    entity: GO:0006952
+references:
+  - citation: Acharya, Troell et al., 2024
+    doi: 10.1016/j.plaphy.2024.108755
+    pmid: 38875777