Repository to host code for the The Pleiotropic Map of Common Genetic Variation and Therapeutic Implications.
Analysis conducted for each manuscript paragraphs are stored under consecutive chapter subdirectory.
The input datasets are downloaded and subsequent datasets are prepared for downstream analysis.
To install all dependencies required to run notebooks run:
make dev
- Python 3.11+
- uv
- Java 11 (recommended using sdkman)
- ~40G of RAM
- ~30G of disk space
- gsutil & gcloud sdk (for downloading data from Google Cloud Storage)
To add new dependency use uv add ${dependency}
All data stored for the purpose of the analysis should be dumped into the data
directory. They are not tracked by the git.