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AI-Powered Genomic Vulnerability Detection Pipeline

GenoSense is a robust, AI-driven genomics platform designed to streamline the flow of genetic data between hospitals, labs, and AI-powered analysis systems. It enables early disease detection, prediction of genetic vulnerabilities, and geographic visualization of common disease trends — all while maintaining strict data privacy through encryption.


ChatGPT Image Apr 20, 2025, 10_02_55 AM

Demo Video Link:

Demo video

Presentation Link:

PPT link here

🚀 Project Overview

This platform facilitates a complete pipeline for genomics-based healthcare prediction and disease mapping:

  1. Hospital Data Submission: Hospitals securely submit patient sample data to the system.
  2. Laboratory Processing: Labs receive sample requests and perform DNA sequencing.
  3. Variant Generation: Sequenced DNA is compared with the Human Genome Reference to extract genetic variants (VCF format).
  4. AI Vulnerability Analysis: The system uses a Hugging Face LLaMA model to analyze variants and predict possible health vulnerabilities.
  5. Human Insight Rendering: Predictions are interpreted and displayed in an easy-to-understand human-readable format.
  6. Geographic Disease Mapping: The system tracks common genetic conditions in nearby regions and displays them on an interactive map.
  7. End-to-End Encryption: All sensitive information (patient identity, DNA data, medical history) is encrypted during transit and storage.

🏥 Hospital Dashboard

  • Submit patient samples to certified labs.
  • Track lab request status.
  • View AI-generated health risk predictions.
  • Explore local disease hotspots based on genomic data.

🧪 Lab Dashboard

  • Accept or reject sequencing requests from hospitals.
  • Upload DNA sequence data and generate VCF variant files.
  • Monitor sample analytics and report predictions back to the hospital.
  • Collaborate with AI models for high-accuracy genome analysis.

🌍 Disease Hotspot Mapping

  • Aggregates anonymized predictions from various hospitals/labs.
  • Displays regions with high frequency of certain genetic vulnerabilities.
  • Helps in identifying and preparing for possible public health concerns.

🔒 Data Privacy & Encryption

  • All sample and patient data is encrypted end-to-end using secure cryptographic protocols.
  • No raw DNA or personal identity is exposed during AI processing.
  • Role-based access control ensures only authorized hospitals and labs interact with relevant data.

🧠 AI Model

  • Built using a fine-tuned LLaMA model from Hugging Face.
  • Accepts VCF variant details and returns interpretable medical insights.
  • Designed to aid genetic counselors, doctors, and patients in understanding potential health risks.

📁 Sample Workflow

graph LR
A[Hospital] -->|Sample Sent| B[Lab]
B -->|DNA Sequencing| C[Generate VCF]
C --> D[AI Model: Predict Vulnerabilities]
D --> E[Hospital Receives Report]
D --> F[Map Common Vulnerabilities on Human Body and also marking common disease of a particular region on map]
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Technology Stack:

  1. Frontend : Swelt
  2. Backend : Go
  3. Machine Learning : Flask , Python

Contributors:

Team Name: CodeNhiAta

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