dna-damage-response

Multi-scale topological machine learning for single-molecule localization microscopy (SMLM) — companion code for a paper on chromatin damage nano-architecture in irradiated cells.

Reproducible computational functional-genomics case study on evidence boundaries in genetic-to-pharmacological target prioritization.

DNA damage and repair transcriptomics integrating DESeq2, race/disease contrasts, metabolism/immunology panels, ashr shrinkage, and GO/KEGG/Reactome enrichment

Cell-type-weighted regulatory prior for DREM over NASA OSDR Arabidopsis pseudo-time-series: a single-cell atlas that acts on the model, not just its annotation. SOG1/MYB3R attribution recovered with a built-in sog1-1 knockout control.

858 Therapeutics — independent third-party profile of a public API surface, by API Evangelist. 858 Therapeutics is a clinical-stage biotechnology company based in San Diego, California, developing first-in-class and best-in-class small-molecule therapies that target tumor dependencies in DNA damage response (DDR) pathways.